Got that sports drink loaded and energy gels ready to go? There is some recent evidence to suggest that many of us are not getting the best out of the exercise we do. Particularly from a general health perspective. A recent review of the body’s energy pathways supports the growing idea that exercising while in a relatively carbohydrate poor state (e.g. when you're hungry first thing in the morning) drives a number of cellular process that improve energy production and efficiency, and could deliver greater health benefits. This includes a reduced risk for metabolic disorders (eg Diabetes) and certain cancers. Some of this action is through a cell protein known as P53, but also through up-regulating fatty transport proteins allowing greater use of fat as an energy source.